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Bisindolylmaleimide IV
CAS No. 119139-23-0
Bisindolylmaleimide IV( —— )
Catalog No. M20912 CAS No. 119139-23-0
Bisindolylmaleimide IV is a protein kinase C (PKC) ?cell permeable inhibitor(?IC50 : 0.10 - 0.55 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 53 | Get Quote |
|
| 5MG | 87 | Get Quote |
|
| 10MG | 140 | Get Quote |
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| 25MG | 282 | Get Quote |
|
| 50MG | 356 | Get Quote |
|
| 100MG | 530 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBisindolylmaleimide IV
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NoteResearch use only, not for human use.
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Brief DescriptionBisindolylmaleimide IV is a protein kinase C (PKC) ?cell permeable inhibitor(?IC50 : 0.10 - 0.55 μM).
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DescriptionBisindolylmaleimide IV is a protein kinase C (PKC) ?cell permeable inhibitor(?IC50 : 0.10 - 0.55 μM).
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In VitroBisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC50 of 0.1 μM in 1 % DMSO, while the IC50 of 0.55 μM in 10 % DMSO.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research Area——
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Indication——
Chemical Information
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CAS Number119139-23-0
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Formula Weight327.34
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Molecular FormulaC20H13N3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (381.87 mM)
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SMILESO=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1c[nH]c2ccccc12
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Chemical Name34-Bis(1H-indol-3-yl)pyrrole-25-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Toullec D Pianetti P Coste H et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.[J]. Journal of Biological Chemistry 1991 24(24):15771-15781.
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